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Plasma cytokine levels in GD patients. (a–d) The levels of plasma IL-21, IL-4, IL-17A, and IFN-γ were detected by ELISA in GD patients (BT: 23; AT: 16) and 20 HC. (e) Relation of PD-1+Tfh with IL-21. (f) Relation of Tfh2 frequency with IL-21 level. (g) Relation of PC frequency with IL-21 level. ∗p < 0.05, ∗∗p < 0.01, and ∗∗∗p < 0.001; ns: no significant difference.
