Table 2.
The main pharmacokinetic parameters of jervine after intravenous administration.
| Parameters | Unit | Jervine |
|---|---|---|
| AUC(0–t) | ng/mL·h | 892.6 ± 285.0 |
| AUC(0–∞) | ng/mL·h | 969.3 ± 277.7 |
| MRT(0–t) | h | 3.2 ± 0.6 |
| MRT(0–∞) | h | 4.4 ± 1.5 |
| t 1/2z | h | 3.4 ± 1.2 |
| CLz/F | L/h/kg | 1.7 ± 0.5 |
| V z/F | L/kg | 8.1 ± 4.0 |
| C max | ng/mL | 506.6 ± 192.8 |