Table 2.
Correlation of LTBP2 protein expression with clinical characteristics of CRC patients.
| Feature | n | LTBP2 | χ 2 | P value | |
|---|---|---|---|---|---|
| Low or no expression | High expression | ||||
| Total | 204 | 146 | 58 | ||
| Gender | 3.559 | 0.059 | |||
| Male | 127 | 85 (66.9%) | 42 (33.1%) | ||
| Female | 77 | 61 (79.2%) | 16 (20.8%) | ||
| Age | 0.001 | 0.976 | |||
| ≤60 | 63 | 45 (71.4%) | 18 (28.6%) | ||
| >60 | 141 | 101 (71.6%) | 40 (28.4%) | ||
| Location | 1.343 | 0.511 | |||
| Right colon | 35 | 23 (65.7%) | 12 (34.3%) | ||
| Left colon | 111 | 83 (74.8%) | 28 (25.2%) | ||
| Rectum | 58 | 40 (69.0%) | 18 (31.0%) | ||
| Differentiation | 0.095 | 0.954 | |||
| Poor | 4 | 3 (75.0%) | 1 (25.0%) | ||
| Well and middle | 194 | 139 (71.6%) | 55 (28.4%) | ||
| Othersa | 6 | 4 (66.7%) | 2 (33.3%) | ||
| TNM stage | 38.118 | <0.001∗ | |||
| 0 and I | 47 | 44 (93.6%) | 3 (6.4%) | ||
| II | 78 | 60 (76.9%) | 18 (23.1%) | ||
| III | 65 | 40 (61.5%) | 25 (38.5%) | ||
| IV | 14 | 2 (14.3%) | 12 (85.7%) | ||
| T stage | 15.953 | <0.001∗ | |||
| Tis, T1, and T2 | 54 | 50 (92.6%) | 4 (7.4%) | ||
| T3, T4 | 150 | 96 (64.0%) | 54 (36.0%) | ||
| N stage | 20.443 | <0.001∗ | |||
| N0 | 128 | 104 (81.2%) | 24 (18.8%) | ||
| N1a | 40 | 26 (65.0%) | 14 (35.0%) | ||
| N1b | 20 | 10 (50.0%) | 10 (50.0%) | ||
| N2a,b | 16 | 6 (37.5%) | 10 (62.5%) | ||
| M stage | 24.24 | <0.001∗ | |||
| M0 | 190 | 144 (75.8%) | 46 (24.2%) | ||
| M1 | 14 | 2 (14.3%) | 12 (85.7%) | ||
| Preoperative CEA (ng/ml) | 4.798 | 0.091 | |||
| ≤5 | 71 | 57 (80.3%) | 14 (19.7%) | ||
| >5 | 78 | 50 (64.1%) | 28 (35.9%) | ||
| Unknown | 55 | 39 (70.9%) | 16 (29.1%) | ||
aMucinous adenocarcinoma, 6 cases. ∗P < 0.05.