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. 2019 Mar 10;2019:4957646. doi: 10.1155/2019/4957646

Figure 4.

Figure 4

Nico decreased LPS-induced HPAEC apoptosis. (a) Effects of Nico on the viabilities of HPAECs were assessed by CCK-8. (b) Hoechst 33342 staining showed that Nico decreased HPAEC apoptosis induced by LPS, and Gli abolished the effects. (c) Nico pretreatment markedly inhibited the expression of c-caspase-3, caspase-9, and CHOP in HPAECs stimulated with LPS, and Gli abolished the effects. Data were shown as mean ± SEM of at least three independent experiments performed in triplicate. Statistically significant differences: ∗P < 0.05 versus the control group; #P < 0.05 versus the LPS group; †P < 0.05 versus the LPS+Nico group. Scale bar: 25 μm.