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The H2-O2 mixture-induced inhibition of ER stress caused by CIH for 35 d: (a) the ER stress markers GRP 78, caspase 12, and CHOP protein expressions; (b–d) the ratios of p-PERK, p-eIF2α/eIF2α, and p-IRE 1/IRE 1 in the left ventricle; (e) ATF 6, ATF 4, and XBP 1 protein expressions. The results are presented as the mean ± SEM. ∗p < 0.05; ∗∗p < 0.01 vs. normoxia group; #p < 0.05 vs. CIH group; n = 3.
