Table 1.
Treatment | Time in week | ||||
---|---|---|---|---|---|
0 | 2 | 4 | 6 | ||
Normal control | 183.00±3.11 | 234.13±7.47 | 269.56±11.43 | 280.00±7.00 | |
| |||||
Diabetic control | 193.42±8..63 | 190.00±5.48N | 181.00±8.21N | 172.00±9.00N | |
| |||||
Diabetic + GBC (5mg/Kg) | 177.00±6.10 | 230.66±4.92∗ | 254.00±7.00∗ | 266.03±8.43 | |
| |||||
Diabetic + Leaf extract | 200mg/Kg | 200.23±5.79 | 210.00.±3.79 | 230.14±8.00 ∗ | 236.87±10.00N |
400mg/Kg | 190.76±7.14 | 240.89±6.84 | 255.76±11.05∗ | 250.88±8.69 |
All the data has been expressed as mean ± SEM of eight independent samples from each group (n = 8) analyzed by SPSS 13.0 version. The treated groups are CN (control normal), DM (diabetic or group II). DM+E200: diabetic rats treated with 200mg/Kg of leaf extract (group III); DM+E400: diabetic rats treated with 400mg/Kg of leaf extract; DM+GBC (group IV): diabetic rats treated with glibenclamide (group V).
N: significant difference from normal control.
∗: significant difference from positive control (untreated diabetic).
@: significant difference from the reference drug, glibenclamide.