Table 2.
Effect of Adansonia digitales leaves extract on blood cholesterol level (mg/dl) of diabetic rats.
| Treatment | Time in week | ||||
|---|---|---|---|---|---|
| 0 | 2 | 4 | 6 | ||
| Normal control | 70.32±1.75 | 74.65±4.27 | 82.56±4.93 | 75.69±4.83 | |
|
| |||||
| Diabetic control | 161.86±3.99N | 168.40±8.11N | 177.61±5.65N | 180.36 ±7.44N | |
|
| |||||
| Diabetic +GBC (5 mg/Kg) | 170.38±5.00N | 140.17±7.66N∗ | 115.45±3.22N∗ | 77.15±3.85∗ | |
|
| |||||
| Diabetic + Leaf extract | 200 mg/Kg | 176.91±9.22N | 169.20±5.88N @ | 154.03±4.64N∗@ | 142.19±5.23N∗@ |
| 400 mg/Kg | 189.00 ± 8.02N | 150.22±3.28N | 133.45±6.57N∗ | 91.78±5.61∗ | |
All the data has been expressed as mean ± SEM of eight independent samples from each group (n = 8) analyzed by SPSS 13.0 version. The treated groups are CN (control normal), DM (diabetic or group II). DM+E200: diabetic rats treated with 200mg/Kg of leaf extract (group III); DM+E400: diabetic rats treated with 400mg/Kg of leaf extract; DM+GBC (group IV): diabetic rats treated with glibenclamide (group V).
N: significant difference from normal control.
∗: significant difference from positive control (untreated diabetic).
@: significant difference from the reference drug, glibenclamide.