Table 3.
Treatment | Time in week | ||||
---|---|---|---|---|---|
0 | 2 | 4 | 6 | ||
Normal control | 57.13±1.70 | 64.18±4.89 | 60.33±2.74 | 55.93±1.06 | |
| |||||
Diabetic control | 150.12±8.0N | 160.55±7.44N | 167.48 ±5.9N | 161.07±3.83N | |
| |||||
Diabetic + GBC (5 mg/Kg) | 144.68±6.34N | 110.00±4.35N∗ | 92.46±3.71N∗ | 68.70±3.38N∗ | |
| |||||
Diabetic + Leaf extract | 200 mg/Kg | 167.20±7.63N | 154.15±4.84N | 145.47±6.56N∗@ | 120.32 ± 5.68N∗@ |
400 mg/Kg | 155.83±7.50N | 136.22±6.25N∗ | 117.19±3.99N∗@ | 91.55 ± 6.00N∗@ |
All the data has been expressed as mean ± SEM of eight independent samples from each group (n = 8) analyzed by SPSS 13.0 version. The treated groups are CN (control normal), DM (diabetic or group II). DM+E200: diabetic rats treated with 200mg/Kg of leaf extract (group III); DM+E400: diabetic rats treated with 400mg/Kg of leaf extract; DM+GBC (group IV): diabetic rats treated with glibenclamide (group V).
N: significant difference from normal control.
∗: significant difference from positive control (untreated diabetic).
@: significant difference from the reference drug, glibenclamide.