Table 2. Prevalence of frailty and adjusted risk of mortality for older patients following ACS and PCI.
Study | Frailty definition | Frailty prevalence | Follow up | Adjusted risk of all-cause mortality |
Alegre, et al.[6] | FRAIL scale | 27.3% | 6 months | HR = 3.82 (95% CI: 1.80–8.11) |
Ekerstad, et al.[8] | CFS | 48.5% | 30 days | OR = 2.17 (95% CI: 1.28–3.67) |
Ekerstad, et al.[9] | CFS | 48.5% | 1 yr | HR = 4.3 (95% CI: 2.4–7.8) |
Kang, et al.[10] | CFS | 43.2% | 4 months | HR = 5.39 (95% CI: 1.48–19.69) |
Myers, et al.[11] | Frailty index | 5.1% | 13 yrs | HR = 2.02 (95% CI: 1.46–2.79) |
Sanchis, et al.[14] | Green score | 47.0% | 25 months | HR = 1.25 (95% CI: 1.15–1.36) |
Salinas, et al.[15] | SHARE-FI | 37.9% | 30 days | Not applicable |
Blanco, et al.[16] | EFS | 20.8% | 1 yr | HR = 4.03 (95% CI: 2.02–8.04) |
Graham, et al.[17] | EFS | 30.0% | 1 yr | HR = 3.49 (95% CI: 1.08–7.61) |
Matsuzawa, et al.[20] | Gait speed | 33% | 5.5 yrs | HR = 0.71 (95% CI: 0.62–0.82) for increase of0.1 m/ second in gait speed |
For all outcomes, the comparator is older people defined as fit. ACS: acute coronary syndrome; CI: confidence interval; CFS: clinical frailty scale; EFS: Edmonton frail scale; HR: hazard ratio; PCI: percutaneous coronary intervention; SHARE-FI: Survey of Health, Ageing and Retirement in Europe Frailty Instrument.