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Lower respiratory tract inflammatory response induced by hRSV infection. Upon hRSV infection in the lower respiratory tract, the epithelial cells secrete IL-6, IFN-γ, CCL3, CCL5, CXCL8, and TSLP among others inflammatory mediators. This inflammatory immune response promotes the infiltration of immune cells (such as monocytes, eosinophil, neutrophils and lymphocytes, among other) into the lungs, causing an obstruction of the airways and damage to the tissue.
