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. 2019 Mar 18;10:527. doi: 10.3389/fmicb.2019.00527

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Copyright © 2019 Sokovic Bajic, Djokic, Dinic, Veljovic, Golic, Mihajlovic and Tolinacki.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The effect of BGZLS10-17 supernatant on the cytokine production. mRNA expression levels of IL-8 stimulated by IL-1β with and without BGZLS10-17 supernatant without GABA, 4 mM bacterial GABA in supernatant, and 4 mM artificial GABA in supernatant (A) and TGF-β expression levels in presence of BGZLS10-17 supernatant containing bacterial GABA in three concentrations (1, 2, and 4 mM) and expression of TGF-β in presence of IL-1β, or IL-1β together with the BGZLS10-17 supernatant containing 4 mM bacterial GABA, and supernatant with addition of 4 mM artificial GABA (B) in differentiated Caco-2 cells. The statistical significance of mRNAs expression is shown (^∗p < 0.05; ^∗∗p < 0.01, ^∗∗∗p < 0.001), bact., bacterial; art., artificial.