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. 2019 Mar 18;10:427. doi: 10.3389/fmicb.2019.00427

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Copyright © 2019 Ragavendran, Manigandan, Kamaraj, Balasubramani, Prakash, Perumal and Natarajan.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Stereo microscopic view of 4th instar (a,b) control larvae of Ae. aegypti and Cx. quinquefasciatus of midgut, thorax, and anal gill parts. (c–f) Ae. aegypti and Cx. quinquefasciatus treated with Penicillium sp. mycelium extract at 500 μg/ml concentration and extract treatment induced toxic effects on many regions of the body (including thorax, abdomen, anal gills, (black arrows) indicates loss of external hairs, crumbled epithelial layer of the outer cuticle and shrinkage of the larvae).