Table 2.
Lesion Characteristics.a
| Baseline RC |
p |
|||||
|---|---|---|---|---|---|---|
| Characteristics | RC2,3 (n=605)b | RC4,5 (n=775)b | RC6 (n=148)b | RC2,3 vs RC4,5 | RC2,3 vs RC6 | RC4,5 vs RC6 |
| Lesion location | ||||||
| ATK only | 293 (48.4) | 207 (26.7) | 40 (27.0) | <0.001 | <0.001 | 0.92 |
| SFA only | 78 (12.9) | 23 (3.0) | 6 (4.1) | <0.001 | 0.001 | 0.45 |
| SFA to popliteal | 99 (16.4) | 86 (11.1) | 13 (8.8) | 0.005 | 0.02 | 0.47 |
| POP only | 116 (19.2) | 98 (12.6) | 21 (14.2) | 0.001 | 0.19 | 0.59 |
| ATK and BTK | 80 (13.2) | 103 (13.3) | 18 (12.2) | >0.99 | 0.79 | 0.79 |
| SFA to BTK | 18 (3.0) | 26 (3.4) | 3 (2.0) | 0.76 | 0.78 | 0.61 |
| POP to BTK | 62 (10.2) | 77 (9.9) | 15 (10.1) | 0.86 | >0.99 | 0.88 |
| BTK only | 232 (38.3) | 464 (59.9) | 89 (60.1) | <0.001 | <0.001 | >0.99 |
| Unknown | 0 (0.0) | 1 (0.1) | 1 (0.7) | >0.99 | 0.20 | 0.30 |
| Target lesion length, mm | 87.9±86.9 (n=562) [59.1, IQR 25.9, 115.0] | 131.3±117.8 (n=727) [86.3, IQR 38.3, 200.4] | 105.8±93.7 (n=137) [82.8, IQR 30.1, 147.6] | <0.001 | 0.03 | 0.02 |
| <40 | 206 (36.7) | 190 (26.1) | 45 (32.8) | <0.001 | 0.43 | 0.12 |
| 40–99 | 185 (32.9) | 190 (26.1) | 31 (22.6) | 0.01 | 0.02 | 0.46 |
| ≥100 | 171 (30.4) | 347 (47.7) | 61 (44.5) | <0.001 | 0.002 | 0.51 |
| Distal RVD, mm | 3.8±1.2 (n=578) [3.7, IQR 2.8, 4.6] | 3.2±1.2 (n=745) [2.9, IQR 2.3, 4.0] | 3.0±1.1 (n=140) [2.7, IQR 2.2, 3.6] | <0.001 | <0.001 | 0.14 |
| Preprocedure MLD, mm | 0.7±0.8 (n=589) [0.5, IQR 0.0, 1.2] | 0.6±0.8 (n=750) [0.2, IQR 0.0, 0.9] | 0.6±0.8 (n=144) [0.5, IQR 0.0, 1.1] | 0.001 | 0.19 | 0.43 |
| Preprocedure stenosis, % | 80.7±19.2 (n=590) [85.0, IQR 66.0, 100.0] | 83.3±19.7 (n=753) [91.0, IQR 70.0, 100.0] | 80.5±20.1 (n=145) [85.0, IQR 65.0, 100.0] | 0.01 | 0.91 | 0.11 |
| Chronic total occlusions | 195/590 (33.1) | 331/753 (44.0) | 57/145 (39.3) | <0.001 | 0.17 | 0.32 |
| TASC lesion type | <0.001 | 0.005 | 0.19 | |||
| A | 366/581 (63.0) | 348/744 (46.8) | 68/142 (47.9) | <0.001 | 0.001 | 0.85 |
| B | 105/581 (18.1) | 129/744 (17.3) | 34/142 (23.9) | 0.77 | 0.12 | 0.08 |
| C | 65/581 (11.2) | 141/744 (19.0) | 20/142 (14.1) | <0.001 | 0.38 | 0.19 |
| D | 45/581 (7.7) | 126/744 (16.9) | 20/142 (14.1) | <0.001 | 0.02 | 0.46 |
| Predominantly calcified plaque | 334/560 (59.6) | 411/717 (57.3) | 85/141 (60.3) | 0.42 | 0.92 | 0.58 |
| PARC category | 0.04 | 0.003 | 0.11 | |||
| Focal | 37/304 (12.2) | 51/366 (13.9) | 5/74 (6.8) | 0.57 | 0.22 | 0.12 |
| Mild | 71/304 (23.4) | 54/366 (14.8) | 6/74 (8.1) | 0.005 | 0.003 | 0.14 |
| Moderate | 78/304 (25.7) | 102/366 (27.9) | 26/74 (35.1) | 0.54 | 0.11 | 0.21 |
| Severe | 118/304 (38.8) | 159/366 (43.4) | 37/74 (50.0) | 0.24 | 0.09 | 0.31 |
| Access site | ||||||
| Femoral | 618/654 (94.5) | 796/852 (93.4) | 149/158 (94.3) | 0.45 | 0.85 | 0.86 |
| Popliteal | 5/654 (0.8) | 4/852 (0.5) | 1/158 (0.6) | 0.51 | >0.99 | 0.57 |
| Tibial | 33/654 (5.0) | 63/852 (7.4) | 5/158 (3.2) | 0.07 | 0.40 | 0.06 |
| Pedal | 8/654 (1.2) | 50/852 (5.9) | 8/158 (5.1) | <0.001 | 0.005 | 0.85 |
| Brachial | 2/654 (0.3) | 1/852 (0.1) | 0/158 (0.0) | 0.58 | >0.99 | >0.99 |
| Device data available (per lesion) | 597 (98.7) | 766 (98.8) | 142 (95.9) | 0.81 | 0.04 | 0.02 |
| Balloons | 578 (96.8) | 740 (96.6) | 141 (99.3) | 0.88 | 0.15 | 0.10 |
| Atherectomy | 437 (73.2) | 494 (64.5) | 107 (75.4) | <0.001 | 0.67 | 0.01 |
| Stent | 120 (20.1) | 111 (14.5) | 25 (17.6) | 0.007 | 0.56 | 0.37 |
| Bailout stent | 27 (4.5) | 34 (4.4) | 0 (0.0) | >0.99 | 0.005 | 0.006 |
| Postprocedure MLD, mm | 2.9±1.2 (n=575) [2.8, IQR 2.0, 3.7] | 2.3±1.2 (n=723) [2.1, IQR 1.5, 3.1] | 2.2±1.2 (n=142) [2.0, IQR 1.4, 2.9] | <0.001 | <0.001 | 0.29 |
| Postprocedure stenosis, % | 29.5±15.9 (n=577) [28.0, IQR 19.0, 37.0] | 33.9±20.8 (n=724) [31.0, IQR 21.0, 41.0] | 35.0±23.5 (n=142) [33.0, IQR 21.0, 43.0] | <0.001 | <0.001 | 0.58 |
Abbreviations: ATK, above the knee; BTK, below the knee; IQR, interquartile range; MLD, minimum lumen diameter; PARC, Peripheral Academic Research Consortium; RC, Rutherford category; RVD, reference vessel diameter; SFA, superficial femoral artery; TASC, Trans-Atlantic Inter-Society Consensus.
a
Continuous data are presented as the mean ± standard deviation [median, IQR Q1, Q3]; categorical data are given as the number (percentage).
b
Number of lesions unless otherwise noted.