Figure 2.
In vitro apparent concentration profiles of CyA from the conventional SEDDS formulations in (a) fasted state simulated gastric fluid (FaSSGF); (b) fed state simulated gastric fluid (FeSSGF); (c) fasted state simulated intestinal fluid (FaSSIF); and (d) fed state simulated intestinal fluid (FeSSIF) medium prepared with different amounts of vehicle components: 900 mg (F1, □), 675 mg (F2, △), and 450 mg (F3, ◊). The amount of drug in each formulation was equivalent to 100 mg, and the data are expressed as mean ± SD (n = 3).