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. 2016 Apr 22;8(4):161. doi: 10.3390/polym8040161

Figure 10.

Figure 10

Hydrolytic release of imiquimod from polymer 5 at 37 °C in acidic environment (citrate buffer, pH 6) (), and enzymatic release of imiquimod from polymer 5 at 37 °C in the same buffer with L-cysteine activated papain (■). The amount of the released drug was estimated using a calibration curve for the free drug.