Figure 15.

Representation of an adaptive resolution simulation in which a high-resolution region (AA region) is coupled to a low-resolution region (CG region). In the AA region, the structure of the molecules are described in their full atomistic details. In the CG region, however, a simpler representation of the structure and interactions of the molecules are utilized. A transition region is used to connect these regions. The novelty as well as difficulty of adaptive resolution schemes depends strongly on the properties of the transition region, i.e., the way molecules change their resolution. Reprinted from Potestio et al. [337] under the terms of the Creative Commons Attribution License.