Figure 1.

A schematic illustration illustrating the normal periodontal tissues (A); injured periodontium in periodontitis (B); and forms of PLGA applied for periodontal regeneration process (C). In (C), PLGA membranes can inhibit the early down-growth of gingival epithelium and connective tissues, allowing regenerative cells to repopulate the denuded root surface; PLGA based scaffolds can provide initial mechanical support and three-dimensional niches for neo-tissue formation; PLGA based delivery carriers can release the biological factors, and antimicrobial drugs to enhance periodontal regeneration.