Table 2.
Examples of redox-stimuli responsive gene delivery systems.
| Polymer used | Type of system | Gene used | Ref. |
|---|---|---|---|
| Disulfide-containing cross-linked polyethylenimines (PEI-SS-CLs) | Polyplexes | pDNA | [84] |
| Hyaluronic acid coated reducible hyperbranched poly-(amidoamine) (RHB) (HA/RHB/pDNA) | Nanoassembly | pDNA | [85] |
| Hyperbranched PAAs with tertiary amino cores and amine, poly(ethylene glycol) (PEG) and hydroxyl terminal groups | Polyplexes | pDNA | [86] |
| mPEG-b-PLL-g-(ss-lPEI) (PLI) | Polyplexes | XIAP siRNA | [87] |
| Bock co-polymer from PLGA-s-s-PEGMA | Core-shell nanoparticle | pDNA | [88] |
| Polyaspartamide-based disulfide-containing brushed polyethylenimine (P(Asp-Az)X-SS-PEIs) | Polyplexes | pDNA | [89] |
| Reducible copolypeptides (rCPP) with HRP(histidine-rich peptide (HRP)) and NLS sequences | Polyplexes | p DNA | [90] |
| SSPEI | Polyplexes | siRNA | [91] |
| Arginine-conjugated poly(cystamine-bis-acrylamide-diaminohexane) (poly(CBA-DAH-R)) | Polyplexes | siRNA | [92] |