Figure 2.

(a) In vivo antitumor effect obtained from treatment with multi-walled carbon nanotubes (MWCNTs), 10-hydroxycamptothecin (HCPT), and saline (control) in a mouse model, expressed as the average values of the relative tumor volume v/v₀ (where v denotes the tumor volume at test time points and v₀ denotes the corresponding initial tumor volume at the beginning of treatment). * p < 0.05 (versus the HCPT injection group at the equivalent dose from the 5th day). (b) Change in body weight of each group during the experiments. Data in (a,b) are presented as mean ± SD (n = 8); (c) Typical photographs of excised sarcomas from mice on the 16th day after treatments with MWCNTs 3 (5 mg/kg equiv.), HCPT injection (5 mg/kg equiv.), and saline. Reprinted with permission from Ref. [14]. Copyright (2016) American Chemical Society.