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. 2016 Dec 6;8(12):422. doi: 10.3390/polym8120422

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© 2016 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC-BY) license (http://creativecommons.org/licenses/by/4.0/).

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Molecules produced by polarized RAW 264.7 macrophages encapsulated under modified alginates. Alginates were layered over activated macrophages and: (A,B) nitrite; (C,D) urea; (E,F) urea:nitrite; and (G,H) TNF-α were measured for dual (A,C,E,G) and single (B,D,F,H) modifications. Arginase activity was measured by removing the alginate layer and lysing the cells. n = 4. Data represent the mean value ± standard deviation. Bars with the same letter (a–d) are not statistically different (p < 0.05) from data points of the same activation.

Molecules produced by polarized RAW 264.7 macrophages encapsulated under modified alginates. Alginates were layered over activated macrophages and: (A,B) nitrite; (C,D) urea; (E,F) urea:nitrite; and (G,H) TNF-α were measured for dual (A,C,E,G) and single (B,D,F,H) modifications. Arginase activity was measured by removing the alginate layer and lysing the cells. n = 4. Data represent the mean value ± standard deviation. Bars with the same letter (a–d) are not statistically different (p < 0.05) from data points of the same activation.