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. 2016 Dec 6;8(12):422. doi: 10.3390/polym8120422

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© 2016 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC-BY) license (http://creativecommons.org/licenses/by/4.0/).

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Synergistic indices for molecules produced by polarized RAW 264.7 macrophages: (A) nitrite; (B) urea; (C) urea:nitrite; and (D) TNF-α for M(LPS), M(IL-4), and M(0) cells were calculated based on previously obtained values for single modifications of alginates [9]. n = 4. Data represent the mean value ± standard deviation. Bars with the same letter (a–d) are not statistically different (p < 0.05) from data points of the same activation. All measured values in panel B were statistically similar.