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. 2017 Feb 21;9(2):76. doi: 10.3390/polym9020076

Table 3.

Examples of polymer-graphene electrospun scaffolds for tissue engineering.

Polymers (and additives) Solvents Nanocarbons Filler loading (wt %) Structure Main improvements Target tissue Refs
CS/GEL/HA AA/H2O GO; RGO 2% Random Bioactivity, antibacterial and mechanical properties Bone [155]
CS/PEO/BC AA/H2O GO 0–2 Random D = 145–254 nm Mechanical properties Skin [153]
CS/PVP/PEO AA/H2O GO 0–2 Random, D = 80–200 nm Mechanical properties, bioactivity Skin/bone [152]
GEL DMSO GO-g-[P(HEMA-g-CL)] 2–3 Random, D = 100–200 nm Mechanical and electrical properties, wettability Not specified [151]
PAN DMF GO; RGO N/A Random Mechanical, electrical properties Not specified [157]
PCL CHCl3 GO N/A Random, D = N/A Mechanical, electrical, cell signaling Skeletal muscle [158]
PCL CHCl3 GO 0.3–2 Random, D = 0.1–8 μm Mechanical, electrical properties, bioactivity Muscle [159]
PCL DMF GO 0.3–0.5 Random; D = 1–3 μm Cell differentiation Nerve/cartilage [8]
PCL DMF GO 0.5–2 Random, D = 0.2–2.5 μm Mechanical properties, bioactivity, biodegradability Bone [160]
PCL DCM/EtOH 4:1 GO; GO-g-PEG 0.25–2 Random, D = 200–1000 nm Mechanical, wettability, cell adhesion Osteochondral [7]
PCL AA GO; RGO 0–1 Aligned, D = 100–400 nm Mechanical properties Not specified [161]
PLA CHCl3/DMF GO; GO-g-PEG 2 Random, D = 500–1000 nm Mechanical properties Osteochondral [28]
PLA/HA DCM/DMF GO 1–3 D = 412–516 nm Mechanical, bioactivity Bone [162]
PLA/PU 4:1 DMF/DCM 2:3 GO 5 Random, D ~ 1 μm Biocompatibility, antimicrobial properties Cartilage [163]
PLGA THF/DMF GO 1 D = 783–1461 nm Wettability, bioactivity Bone [164]
PLGA/Col HFIP GO 4 Random, D = 100–950 nm Cell proliferation, mechanical properties Bone/muscle [124]
PLGA/RGD HFIP GO N/A Random, D = 200–1440 nm myogenic differentiation Bone/muscle [123]
PLGA/SF HFIP GO 1 Random, D = 130–280 nm Mechanical, wettability, cell differentiation Bone [165]
PLLA HFIP GO N/A Aligned; D = 680 nm Cell differentiation and growth Nerve [166]
PU DMF GO 0.5-2 D = 290–400 nm Mechanical properties, bioactivity Osteochondral [167]
PVA H2O GNS 1%–7% Random, D = 200-800 nm Electrical properties Cartilage [168]
PVA H2O GO 0-5 Random, D < 1 μm Mechanical properties, bioactivity Bone [169]
PVA/CS AA/H2O GO 0.05–0.6 D = 123–200 nm Mechanical properties Skin [156]
PVC; FN THF/DMF (4:1) GO; RGO N/A N/A Mechanical, electrical properties, bioactivity Nerve [170]
SF H2O GO; RGO N/A D = 3.9–5.2 μm Electrical properties Nerve [154]

N/A: Data not available; D: Diamater; The other acronyms are available in the acronym list.