Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2019 Mar 7;146(5):dev172361. doi: 10.1242/dev.172361

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2019. Published by The Company of Biologists Ltd

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

PMC Copyright notice

Fig. 4. — Kidney micro-organoids provide a better platform for efficient hPSC-derived kidney cell scale-up. (A) Bright-field image of standard kidney organoid at day 7+11 (left), confocal immunofluorescence image (tile scan) of entire standard organoid showing the spatial restriction of nephron structures to the edge of the organoid (middle), and magnified image of the boxed area showing a nephron within that organoid (right). (B) Bright-field image of kidney micro-organoids (left) and magnified bright-field image of the boxed area, showing a single kidney micro-organoid (middle), and confocal immunofluorescence image of kidney micro-organoids at day 7+11 (right). (C) Change in size of the organoids at different stages of development. (D) Fold change in cell number (and scalable capacity) of micro-organoids compared with standard organoid over time. Scale bars: 500 µm (A, left); 200 µm (A, middle and right, B).