Table 1.
Aidi Injection Used |
|||||
---|---|---|---|---|---|
No (N = 2950) |
Yes (N = 2122) |
||||
Variable | n | % | n | % | P a |
Gender | <.001 | ||||
Female | 1168 | 39.6 | 995 | 46.9 | |
Male | 1782 | 60.4 | 1127 | 53.1 | |
Age, years | |||||
⩽60s | 1350 | 45.8 | 1090 | 51.4 | <.001 |
>60 | 1600 | 54.2 | 1032 | 48.6 | |
Mean ± SD | 59.7±10.8 | 59.2 ± 11.6 | .296 | ||
Body mass index, kg/m2 | |||||
<18.5 | 439 | 14.9 | 346 | 16.3 | .146 |
18.5-24 | 1962 | 66.5 | 1419 | 66.9 | |
>24 | 549 | 18.6 | 357 | 16.8 | |
Tumor type | <.001 | ||||
Gastric cancer | 1482 | 50.2 | 1022 | 48.2 | |
Lung cancer | 636 | 21.6 | 372 | 17.5 | |
Breast cancer | 350 | 11.9 | 326 | 15.4 | |
Colorectal cancer | 270 | 9.2 | 245 | 11.5 | |
Cardias and esophageal cancer | 119 | 4.0 | 87 | 4.1 | |
Hepatobiliary cancer | 34 | 1.2 | 24 | 1.1 | |
Ovarian cancer | 59 | 2.0 | 46 | 2.2 | |
TNM stage | .163 | ||||
I-II | 444 | 15.1 | 350 | 16.5 | |
III-IV | 2506 | 84.9 | 1772 | 83.5 | |
Node metastasis | <.001 | ||||
Negative | 1639 | 55.6 | 1325 | 62.4 | |
Positive | 1311 | 44.4 | 797 | 37.6 | |
Distant metastasis | <.001 | ||||
Negative | 1771 | 60.0 | 1454 | 68.5 | |
Positive | 1179 | 40.0 | 668 | 31.5 | |
Prior chemotherapy | <.001 | ||||
No | 1742 | 59.1 | 1041 | 49.1 | |
Yes | 1208 | 40.9 | 1081 | 50.9 | |
Prior radiotherapy | <.001 | ||||
No | 2792 | 94.6 | 2096 | 98.8 | |
Yes | 158 | 5.4 | 26 | 1.2 | |
ECOG score | .038 | ||||
0-1 | 2822 | 95.7 | 2003 | 94.4 | |
⩾2 | 158 | 5.4 | 119 | 5.6 | |
Comorbidity | |||||
Hypertension | 385 | 13.1 | 268 | 12.6 | .659 |
Renal insufficiency | 33 | 1.1 | 66 | 3.1 | <.001 |
Hepatic insufficiency | 495 | 16.8 | 375 | 17.7 | .406 |
Diabetes | 136 | 4.6 | 111 | 5.2 | .311 |
Chemotherapy regimen | <.001 | ||||
Platinum and fluorouracil based | 1370 | 46.4 | 1006 | 47.4 | |
Platinum and pemetrexed based | 215 | 7.3 | 166 | 7.8 | |
Irinotecan and fluorouracil based | 266 | 9.0 | 201 | 9.5 | |
Platinum and taxane based | 681 | 23.1 | 463 | 21.8 | |
Cyclophosphamide and adriamycin based | 157 | 5.3 | 157 | 7.4 | |
Targeted therapy and others regimen | 261 | 8.8 | 129 | 6.1 | |
Other Chinese medicine | |||||
ShenqiFuzheng injection | 827 | 28.0 | 756 | 35.6 | <.001 |
Glycopeptide injection | 764 | 25.9 | 645 | 30.4 | <.001 |
Kushen injection | 457 | 15.5 | 292 | 13.8 | .087 |
Shenmai Injection | 271 | 9.2 | 168 | 7.9 | .113 |
DiyuShengbai tablet | 161 | 5.5 | 143 | 6.7 | .058 |
Chemotherapy cycles | <.001 | ||||
1-3 | 1777 | 60.2 | 1402 | 66.1 | |
>3 | 1173 | 39.8 | 720 | 33.9 |
Abbreviation: ECOG, Eastern Cooperative Oncology Group.
Boldfaced P values are statistically significant.