Table 3.
Aidi injection used |
|||||
---|---|---|---|---|---|
No (N = 1600) |
Yes (N = 1600) |
||||
Toxicity | n | % | n | % | P a |
Short cycle (1-3) | 1049 | 65.6 | 1055 | 65.9 | |
AST elevation | 114 | 10.9 | 80 | 7.6 | .009 |
ALT elevation | 162 | 15.4 | 96 | 9.1 | <.001 |
CR elevation | 30 | 2.9 | 16 | 1.5 | .035 |
Nausea, vomiting | 463 | 43.9 | 367 | 34.8 | <.001 |
Diarrhea | 93 | 8.9 | 52 | 4.9 | <.001 |
Constipation | 69 | 6.6 | 54 | 5.1 | .154 |
Allergy | 41 | 3.9 | 38 | 3.6 | .711 |
Long cycle (>3) | 551 | 34.4 | 545 | 34.1 | |
AST elevation | 99 | 17.9 | 74 | 13.6 | .046 |
ALT elevation | 114 | 20.7 | 83 | 15.2 | .019 |
CR elevation | 49 | 8.5 | 30 | 5.5 | .030 |
Nausea, vomiting | 293 | 53.2 | 227 | 41.7 | <.001 |
Diarrhea | 74 | 13.4 | 42 | 7.7 | .002 |
Constipation | 51 | 9.2 | 39 | 7.2 | .205 |
Allergy | 55 | 6.4 | 26 | 4.8 | .254 |
Abbreviations: AST, aspartate aminotransferase; ALT, alanine aminotransferase; CR creatinine.
Boldfaced P values values are statistically significant.