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. 2018 Nov 27;18:1534735418810799. doi: 10.1177/1534735418810799

Table 3.

Chemotherapy-Related Toxicity.

Aidi injection used
No (N = 1600)
Yes (N = 1600)
Toxicity n % n % P a
Short cycle (1-3) 1049 65.6 1055 65.9
 AST elevation 114 10.9 80 7.6 .009
 ALT elevation 162 15.4 96 9.1 <.001
 CR elevation 30 2.9 16 1.5 .035
 Nausea, vomiting 463 43.9 367 34.8 <.001
 Diarrhea 93 8.9 52 4.9 <.001
 Constipation 69 6.6 54 5.1 .154
 Allergy 41 3.9 38 3.6 .711
Long cycle (>3) 551 34.4 545 34.1
 AST elevation 99 17.9 74 13.6 .046
 ALT elevation 114 20.7 83 15.2 .019
 CR elevation 49 8.5 30 5.5 .030
 Nausea, vomiting 293 53.2 227 41.7 <.001
 Diarrhea 74 13.4 42 7.7 .002
 Constipation 51 9.2 39 7.2 .205
 Allergy 55 6.4 26 4.8 .254

Abbreviations: AST, aspartate aminotransferase; ALT, alanine aminotransferase; CR creatinine.

a

Boldfaced P values values are statistically significant.