Table 3.
Complications of therapeutic plasma exchange.
| TPE complications/TPE replacement solutions | Albumin 5%, n=39 | Albumin 5% plus Fresh frozen plasma, n=8 | 4% succinylated gelatin, n=10 | Fresh frozen plasma, n=9 | Total, n=66 | p value |
|---|---|---|---|---|---|---|
| Bleeding | 11 (28.2) | 4 (50) | 0 (0) | 2 (22.2) | 17 (25.8) | 0.087 |
| Thrombosis | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 0 |
| Hydroelectrolytic disorders | 1 (2.6) | 2 (25) | 1 (10) | 0 (0) | 4 (6.1) | 0.067 |
| Hypotension | 1 (2.6) | 1 (12.5) | 2 (20) | 2 (22.2) | 6 (9.1) | 0.055 |
| Allergies | 0 (0) | 1 (12.5) | 0 (0) | 0 (0) | 1 (1.5) | 0.121 |
| Arrhythmias | 1 (2.6) | 0 (0) | 1 (10) | 0 (0) | 2 (3) | 0.655 |
| Infections 14 days posterior to TPE | 5 (12.8) | 6 (75) | 3 (30) | 4 (44.4) | 18 (27.3) | 0.002 |
| Catheter-Related Infections | 0 (0) | 0 (0) | 1 (10) | 1 (11) | 2 (3) | |
| Type of infection | ||||||
| Bacterial infection | 4 (80) | 5 (83.3) | 3 (100) | 4 (100) | 16 (88.9) | |
| Bacterial and Mycobacterial | 0 (0) | 1 (16.7) | 0 (0) | 0 (0) | 1 (5.6) | |
| infection | ||||||
| Viral infection | 1 (20) | 0 (0) | 0 (0) | 0 (0) | 1 (5.6) |
TPE: therapeutic plasma exchange.