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Widespread distribution of GDNF in the rat striatum. Photomicrographs of widespread GDNF immunoreactivity in the striatum of rats implanted with the lower dose GDNF-secreting device (a) and associated immunoreactivity in the substantia nigra (c). Histograms of the mean (±SEM) of the volume (b) and optical density (d) of GDNF staining. ∗p < 0.05.
