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Performance in all the cylinder, placing, and stepping tests is significantly impaired at 2 and 4 weeks following intrastriatal injections of QA. In contrast, performance on each of these tests is preserved, in a dose-related manner, by EC-GNDF implants with the higher dose-treated animals performing comparably to presurgery levels (preimplantation and prelesion). ∗p < 0.05; ∗∗p < 0.01; ∗∗∗p < 0.001.
