Table 2.

ROFA-induced lung inflammation: after both five (ROFA-5d) and fifteen instillations (ROFA-15d), mice presented an increase in the number of neutrophils and inflammatory cells that express nNOS and iNOS around airways and in distal lung parenchyma. The macrophages were significantly increased only in ROFA-15d groups compared to saline. ∗P<0.05 compared to saline.

	Airway		Distal lung parenchyma
	Macrophage	Neutrophils	Macrophage	Neutrophils
SAL	3.9±0.5	3.2±1.1	7.8±0.98	9.4±1.5
ROFA-5d	10.7±6.5	8.3±1.4∗	8.3±1.4	18.9±1.8∗
ROFA-15d	9.0±1.0∗	8.3±1.9∗	14.16±1.71∗	22.3±1.9∗