Figure 4.

Effects of DEHP and DiNP on gestational index. Adult female CD-1 mice were orally dosed for 10 days with either vehicle control (corn oil), DEHP (20 µg/kg/day–200 mg/kg/day), or DiNP (20 µg/kg/day–200 mg/kg/day). Females were mated with untreated male mice for breeding trials immediately post-dosing (Panel A, n = 11–23 mice/group), 3 months post-dosing (Panel B, n = 6–21 mice/group), and 9 months post-dosing (Panel C, n = 6–18 mice/group). The gestational index was calculated by dividing the number of females who gave birth to pups by the number of females who successfully achieved pregnancy and multiplying by 100. Data are represented as percentages.