Figure 5.

Effects of DEHP and DiNP on gestation length. Adult female CD-1 mice were orally dosed for 10 days with either vehicle control (corn oil), DEHP (20 µg/kg/day–200 mg/kg/day), or DiNP (20 µg/kg/day–200 mg/kg/day). Females were mated with untreated male mice for breeding trials immediately post-dosing (Panel A, n = 8–20 mice/group), 3 months post-dosing (Panel B, n = 3–17 mice/group), and 9 months post-dosing (Panel C, n = 6–14 mice/group). Gestation length was calculated by using the day a copulatory plug was observed as day 0.5 of pregnancy. Data are represented as means ± SE. Borderline statistical significance (.05 < p ≤ .10) is denoted with a caret (^).