Figure 6.

Effects on DEHP and DiNP on the ability of females to produce pups. Adult female CD-1 mice were orally dosed for 10 days with either vehicle control (corn oil), DEHP (20 µg/kg/day–200 mg/kg/day), or DiNP (20 µg/kg/day–200 mg/kg/day). Females were mated with untreated male mice for breeding trials immediately post-dosing (Panel A, n = 11–23 mice/group), 3 months post-dosing (Panel B, n = 11–22 mice/group), and 9 months post-dosing (Panel C, n = 11–22 mice/group). The percent of females who gave birth was calculated by dividing the number of females who produced pups by the total number of females in that treatment group and multiplying by 100. Data are represented as percentages. Statistically significant difference when compared with control (p ≤ .05) is denoted with an asterisk (*). Borderline statistical significance (.05 < p ≤ .10) is denoted with a caret (^).