Table 1.
Demographic characteristics of study participants at baseline. Data were means ± s.d. or medians (interquartile ranges) for skewed variables or numbers (proportions) for categorical variables.
Sitagliptin (N = 93) | Vildagliptin (N = 94) | Saxagliptin (N = 90) | P value | |
---|---|---|---|---|
Age (years) | 55.1 ± 9.3 | 49.3 ± 10.0 | 48.7 ± 11.2 | 0.02 |
BMI (kg/m2) | 27.0 ± 3.4 | 26.8 ± 3.1 | 27.1 ± 2.9 | 0.93 |
TC (mmol/L) | 5.1 (4.4–5.6) | 5.0 (4.2–5.5) | 5.1 (4.6–6.0) | 0.74 |
LDL-C (mmol/L) | 3.3 ± 0.8 | 3.0 ± 0.9 | 3.3 ± 0.9 | 0.56 |
HDL-C (mmol/L) | 1.2 ± 0.3 | 1.3 ± 0.5 | 1.3 ± 1.2 | 0.87 |
FPG (mmol/L) | 8.3 ± 1.6 | 9.0 ± 2.6 | 8.4 ± 1.6 | 0.40 |
PPG (mmol/L) | 14.9 ± 4.9 | 16.1 ± 5.5 | 13.3 ± 4.6 | 0.17 |
HbA1c (%) | 7.10 (6.70–7.80) | 7.50 (6.90–8.00) | 7.40 (6.80–7.90) | 0.26 |
ALT (IU/L) | 22.1 (16.0–31.5) | 20.0 (17.1–32.0) | 24.0 (19.2–38.0) | 0.11 |
AST (IU/L) | 18.0 (15.0–23.0) | 17.0 (14.4–22.0) | 20.0 (16.0–26.0) | 0.68 |
Cr (µmol/L) | 64.4 ± 16.4 | 67.61 ± 17.0 | 62.2 ± 10.3 | 0.41 |
BIL (µmol/L) | 19.6 ± 30.6 | 14.2 ± 6.5 | 16.4 ± 6.4 | 0.61 |
WBC (109/L) | 5.9 ± 1.0 | 6.5 ± 1.4 | 6.5 ± 1.7 | 0.24 |
P value was calculated for Chi-square test across the three groups.
BIL, total bilirubin; BMI, body mass index; Cr, creatine; FPG, fasting plasma glucose; HbA1c, hemoglobin A1c; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; TC, total cholesterol; WBC, white blood cell.