Skip to main content
. 2019 Mar 21;15:721–729. doi: 10.2147/NDT.S174728

Table 5.

Influence of ZNF804A rs1344706 on brain structure (CMA)

Indices Region Population Model Effect size Heterogeneity Egger’s regression intercept Publication bias
Z P-value D 95% CI I2 P-value T P-value
Gray matter Frontal HC Random −2.008 0.045 −0.740 −1.463~–0.018 89.022 0.000 15.644 0.004 Yes
SZ Fixed 3.445 0.001 0.778 0.336~1.221 60.166 0.057 1.185 0.358 No
Temporal HC Fixed −6.099 0.000 −0.958 −1.266~–0.650 17.898 0.301 2.967 0.097 No
SZ Random 2.140 0.032 0.302 0.025~0.579 89.678 0.000 0.120 0.916 No
Parietal SZ Fixed 5.346 0.000 1.124 0.712~1.537 0.000 0.923
Occipital HC Fixed −3.106 0.002 −0.631 −1.030~–0.233 33.581 0.220
SZ Fixed 3.605 0.000 0.748 0.342~1.155 54.182 0.140
Limbic system HC Random −1.485 0.138 −0.900 −2.087~0.288 93.838 0.000 11.921 0.053 No
SZ Fixed 4.765 0.000 0.939 0.553~1.325 0.000 0.631
Basal nuclei SZ Fixed 4.689 0.000 0.952 0.554~1.350 0.000 0.869
White matter All HC Random 0.081 0.936 0.018 −0.430~0.467 80.609 0.000 1.325 0.256 No
SZ Random −0.295 0.768 −0.087 −0.667~0.492 79.300 0.008 4.468 0.140 No

Abbreviations: CMA, Comprehensive Meta-Analysis; HC, healty control; SZ, schizophrenia.