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. 2019 Mar 22;7:e6645. doi: 10.7717/peerj.6645

Table 2. Top 10 GO_BP terms in each datasets ordered by FDR.

Count: number of genes enriched in the corresponding pathway; FDR, false discovery rate.

GO ID Biological process Count FDR
GSE6764-HCV
GO:0030198 Extracellular matrix organization 59/196 8.35E−17
GO:0060337 Type I interferon signaling pathway 33/64 3.82E−16
GO:0006955 Immune response 88/421 7.84E−15
GO:0051607 Defense response to virus 47/165 9.18E−12
GO:0060333 Interferon-gamma-mediated signaling pathway 30/71 1.73E−11
GO:0007155 Cell adhesion 79/459 2.87E−08
GO:0007165 Signal transduction 144/1,161 9.27E−06
GO:0050900 Leukocyte migration 31/122 1.34E−05
GO:0045071 Negative regulation of viral genome replication 17/40 2.56E−05
GO:0042493 Response to drug 53/304 5.86E−05
GSE49541-NAFLD
GO:0030198 Extracellular matrix organization 29/196 6.55E−18
GO:0007155 Cell adhesion 37/459 7.26E−15
GO:0030574 Collagen catabolic process 13/64 6.27E−08
GO:0030199 Collagen fibril organization 9/39 5.87E−05
GSE84044-HBV
GO:0006955 Immune response 87/421 2.1693E−16
GO:0007155 Cell adhesion 81/459 7.1809E−11
GO:0030198 Extracellular matrix organization 46/196 2.2322E−09
GO:0070374 Positive regulation of ERK1 and ERK2 cascade 38/175 2.6745E−06
GO:0070098 Chemokine-mediated signaling pathway 23/71 3.4269E−06
GO:0002250 Adaptive immune response 33/148 1.927E−05
GO:0060326 Cell chemotaxis 21/65 2.1359E−05
GO:0006954 Inflammatory response 58/379 9.3052E−05
GO:0002548 Monocyte chemotaxis 16/42 0.00015641
GO:0030574 Collagen catabolic process 19/64 0.00052759