Table 2. Top 10 GO_BP terms in each datasets ordered by FDR.
Count: number of genes enriched in the corresponding pathway; FDR, false discovery rate.
GO ID | Biological process | Count | FDR |
---|---|---|---|
GSE6764-HCV | |||
GO:0030198 | Extracellular matrix organization | 59/196 | 8.35E−17 |
GO:0060337 | Type I interferon signaling pathway | 33/64 | 3.82E−16 |
GO:0006955 | Immune response | 88/421 | 7.84E−15 |
GO:0051607 | Defense response to virus | 47/165 | 9.18E−12 |
GO:0060333 | Interferon-gamma-mediated signaling pathway | 30/71 | 1.73E−11 |
GO:0007155 | Cell adhesion | 79/459 | 2.87E−08 |
GO:0007165 | Signal transduction | 144/1,161 | 9.27E−06 |
GO:0050900 | Leukocyte migration | 31/122 | 1.34E−05 |
GO:0045071 | Negative regulation of viral genome replication | 17/40 | 2.56E−05 |
GO:0042493 | Response to drug | 53/304 | 5.86E−05 |
GSE49541-NAFLD | |||
GO:0030198 | Extracellular matrix organization | 29/196 | 6.55E−18 |
GO:0007155 | Cell adhesion | 37/459 | 7.26E−15 |
GO:0030574 | Collagen catabolic process | 13/64 | 6.27E−08 |
GO:0030199 | Collagen fibril organization | 9/39 | 5.87E−05 |
GSE84044-HBV | |||
GO:0006955 | Immune response | 87/421 | 2.1693E−16 |
GO:0007155 | Cell adhesion | 81/459 | 7.1809E−11 |
GO:0030198 | Extracellular matrix organization | 46/196 | 2.2322E−09 |
GO:0070374 | Positive regulation of ERK1 and ERK2 cascade | 38/175 | 2.6745E−06 |
GO:0070098 | Chemokine-mediated signaling pathway | 23/71 | 3.4269E−06 |
GO:0002250 | Adaptive immune response | 33/148 | 1.927E−05 |
GO:0060326 | Cell chemotaxis | 21/65 | 2.1359E−05 |
GO:0006954 | Inflammatory response | 58/379 | 9.3052E−05 |
GO:0002548 | Monocyte chemotaxis | 16/42 | 0.00015641 |
GO:0030574 | Collagen catabolic process | 19/64 | 0.00052759 |