Appendix Table 2.
Multivariable Regression Coefficients for ALM and ALM:BMI
| ALM | ALM | ALM:BMI | ||||||
|---|---|---|---|---|---|---|---|---|
| Model 1 | Model 3 | Model1 | Model 3 | |||||
| Variable | β ± se | p | β ± se | p | β ± se | p | β ± se | p |
| Non-Fasting | ||||||||
| Systolic | −0.152±0.057 | <0.001 | −0.266±0.096 | 0.02 | −13.1±3.73 | 0.001 | −19.9±4.38 | <0.001 |
| Diastolic | 0.075±0.077 | 0.34 | 0.064±0.086 | 0.50 | 5.74±2.76 | 0.04 | 9.42±3.64 | 0.013 |
| Cholesterol | ||||||||
| Total | −0.634±0.181 | 0.001 | −0.811±0.246 | 0.004 | −5.87±8.72 | 0.50 | 1.08±11.15 | 0.10 |
| HDL-C | −0.885±0.079 | <0.001 | −0.928±0.08 | <0.001 | 13.1±2.69 | <0.001 | −13.1±3.30 | <0.001 |
| Triglycerides | 2.775±0.403 | <0.001 | 2.89±0.480 | <0.001 | −100.6±14.26 | <0.001 | −31.3±22.5 | 0.17 |
| ln triglycerides | 0.0183±0.12 | <0.001 | 0.018±0.003 | <0.001 | −0.722±0.079 | <0.001 | −0.099±0.106 | 0.35 |
| Glucose | 0.980±0.168 | <0.001 | 0.454±0.108 | <0.001 | −29.0±7.34 | <0.001 | −15.7±10.6 | 0.15 |
| Inflammatory | ||||||||
| C-reactive protein | 0.0011±0.0045 | 0.82 | −0.010±0.005 | 0.58 | −0.77±0.14 | <0.001 | −0.675±0.237 | 0.007 |
| ln CRP | 0.0312±0.0052 | <0.001 | 0.0031±0.006 | <0.001 | −2.40±0.247 | <0.001 | −0.914±0.335 | 0.009 |
| Fibrinogen | 0.779±0.456 | 0.09 | −0.775±0.504 | 0.30 | −107.0±20.0 | <0.001 | −58.0±29.5 | 0.06 |
| Fasting Variables | ||||||||
| HOMA-IR | 0.324±0.055 | <0.001 | 0.120±0.020 | <0.001 | −6.59±1.88 | 0.001 | −0.205±3.09 | 0.95 |
| HOMA-B | 6.86±1.20 | <0.001 | 1.947±1.03 | <0.001 | −32.8±83.7 | 0.70 | 147.4±104.4 | 0.17 |
| Triglycerides | 1.47±1.07 | 0.18 | 1.13±0.406 | 0.01 | −93.4±19.2 | <0.001 | −13.7±32.4 | 0.68 |
| Ln trig | 0.0085±0.006 | 0.19 | 0.0127±0.006 | 0.01 | −0.585±0.108 | <0.001 | 0.012±0.19 | 0.95 |
| Insulin | 0.937±0.169 | <0.001 | 0.846±0.180 | <0.001 | −21.9±5.99 | 0.001 | −0.218±8.6 | 0.98 |
| LDL-Cholesterol | 0.008±0.35 | 0.98 | −0.370±0.417 | 0.87 | −2.11±12.8 | 0.87 | 27.3±21.9 | 0.22 |
All values represented are from multivariable linear regression models (β coefficient ± standard error) with p-values.
Values bolded are considered statistically significant
Model 1: adjusted for age, sex race, education, smoking status, arthritis
Model 2: Model 1 co-variates, cancer and diabetes
Interaction (Ix): interaction term obesity (Body Fat) term x ASM with model 1 co-variates
Abbreviations: ALM: Appendicular lean mass; BMI: body mass index; HDL-C: high density lipoprotein cholesterol; HOMA: homeostatic assessment model; IR: insulin resistance; Ix: interaction; LDL-C: low density lipoprotein cholesterol; S-sensitivity; s.e.: standard error.
Natural log transformation was used for triglycerides and C-reactive protein