Table 2.
Association of HLA region SNPs with type 2 diabetes, adjusted for age and sex
| SNP | Diabetes prevalence (%) by SNP genotype | ORa | 95% CI | p value | ||
|---|---|---|---|---|---|---|
| 11 | 12 | 22 | ||||
| rs3135377 | 28.7 | 43.2 | 0.53 | 0.15–1.81 | 0.3093 | |
| rs9268852 | 28.1 | 36.3 | 44.4 | 0.71 | 0.56–0.90 | 0.0038 |
| rs9268856 | 33.6 | 39.9 | 44.6 | 0.82 | 0.68–0.97 | 0.0222 |
| rs9268858 | 30.8 | 45.6 | 42.7 | 1.07 | 0.85–1.34 | 0.5694 |
| rs7766843 | 34.2 | 41.2 | 44.3 | 0.86 | 0.72–1.03 | 0.1050 |
| rs9270986 | 28.4 | 38.8 | 44.3 | 0.78 | 0.62–0.98 | 0.0345 |
| rs502771 | 36 | 41.6 | 44.1 | 0.88 | 0.76–1.03 | 0.1080 |
| rs9271720 | 27.7 | 45.4 | 42.6 | 1.02 | 0.85–1.23 | 0.8255 |
| rs9272219 | 32.6 | 44.2 | 42.9 | 1.02 | 0.80–1.28 | 0.9004 |
| rs9272346 | 100 | 22.8 | 43.3 | 0.38 | 0.16–0.93 | 0.0342 |
| rs9272723 | 25.9 | 43.5 | 0.45 | 0.20–1.02 | 0.0563 | |
| rs9273363 | 42.2 | 47.6 | 43.2 | 1.16 | 0.89–1.50 | 0.2726 |
| rs12216336 | 47.3 | 41.9 | 42.8 | 1.00 | 0.82–1.20 | 0.9620 |
a
Allele 1 is the reference for the odds ratio