Table 4:

Associations of maternal factors with log-transformed breastmilk adiponectin at 1- and 3 months postpartum^a

		Crude Modelb				Adjusted Modelc
Models	Maternal Factors	N	β	SE	P	N	β	SE	p
Model 1	Pre-pregnancy BMI, (kg/m2)	135	−0.067	0.028	0.020	130	−0.070	0.030	0.020
	Pre-pregnancy BMI, (kg/m2) *Time	135	0.052	0.020	0.011	130	0.040	0.020	0.045
Model 2	Excessive GWGc,d	135	0.033	0.057	0.564	130	0.078	0.057	0.171
	Excessive GWG * Time	135	−0.024	0.040	0.546	130	−0.001	0.038	0.720
Model 3	OGCT (g/dl)d,e	134	−0.051	0.028	0.073	129	−0.044	0.029	0.131
	OGCT * Time	134	−0.007	0.020	0.719	129	−0.016	0.019	0.391
Model 4	Post-partum weight loss (kg)d,f	132	0.007	0.027	0.792	129	0.009	0.026	0.733
	Post-partum weight loss (kg) * Time	132	−0.019	0.022	0.387	129	−0.006	0.020	0.773

^aAll continuous independent variables (pre-pregnancy BMI, Oral glucose challenge test and post-partum weight loss) were standardized to a mean of 0 and a standard deviation of 1. Bolded values are statistically significant at p-value < 0.05. Time was the time point for measurement of milk hormones (1 and 3 months, with 1 month as the referent)

^bAdjusts for maternal age, maternal education, mode of delivery, breast milk feeding exclusivity, infant sex, gestational age at delivery, and breastmilk volume

^cGestational Weight Gain; excessive gain based on Institute of Medicine 2009 guidelines for gestational weight gain

^dModels additionally adjusted for pre-pregnancy BMI

^eOral Glucose Challenge Test, 50 g glucose challenge administered between 24-28 weeks of gestation to screen for gestational diabetes

^fPost-partum weight loss was calculated as maternal weight at delivery minus maternal weight at 1 or 3 months post-partum, entered into the mixed models as a time varying independent variable.