Table 1.
Baseline characteristics of the study population
| Demographic | Number (n=66) |
|---|---|
| Age (years) | 6.1 (0.47 – 17.6) |
| Weight (kg) | 21 (7.2 – 99.0) |
| Height (cm) | 111.8 (66.0–177.0) |
| Serum Creatinine (mg/dL) | 0.30 (0.10 – 3.1) |
| eGFR (mL/min/1.73m2) | 168.7 (40.0 – 566.5) |
| ALT (U/L) b | 27.0 (6.0–193.0) |
| Duration on study > 10 days | |
| yes | 34 (52%) |
| no | 32 (48%) |
| Gender | |
| Male | 41 (62%) |
| Female | 25 (38%) |
| Race | |
| Caucasian | 53 (80%) |
| African American | 6 (9%) |
| Multiracial | 5 (8%) |
| Asian | 2 (3%) |
| Ethnicity | |
| Not Hispanic | 42 (64%) |
| Hispanic | 24 (36%) |
| Received concomitant midazolam | |
| yes | 64 (97%) |
| no | 2 (3%) |
Values are expressed as either median (range) or as a count (percentage). ALT = Alanine aminotransferase; eGFR = estimated glomerular filtration rate determined by the Schwartz equation.
a
A total of 3 subjects were missing height information and heights were imputed
b
A total of 18 subjects were missing ALT information