Table 1.

Reported NHERF1 phosphorylation sites

Amino acid residue numbering corresponds to human NHERF1. CFTR is cystic fibrosis transmembrane conductance regulator.

Site	Kinase	Proposed function	Refs.
Ser77, Thr95	PKC	Renal phosphate transport	28, 29, 102
Thr156	Akt	Cell division	30
Thr156	RSK1	Nuclear localization	31
Ser162	PKC	CFTR gating	32
Ser280/Ser302	Cdc2	Cell division	33, 34, 103
		CFTR expression
Ser290	GRK6a	Unknown	35
Ser339/Ser340	PKC	NHERF1 oligomerization and CFTR macromolecular assembly	36, 37