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In vivo anti-PD1 treatment induced PD-L1 expression through IFN-γ associated with JAK-STAT pathway in EL4 tumors.
Notes: (A) IFN-γ concentration is higher in treatment group than the control (120 vs 444.1 pg/mL, P<0.05). (B) PD-L1, p-JAK2, p-STAT1 protein expression in IHC was evaluated. Scale bar 50 μm; magnification ×400.
