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. 2019 Mar 19;11:2225–2231. doi: 10.2147/CMAR.S193567

Table 5.

Univariate and multivariate analyses for OS outcomes

Characteristics of patient OS
HR 95% CI P-value

Univariate analysis
Age (years)
 ≥60 vs <60 1.297 1.065–1.581 0.010
Sex
 Male vs female 0.457 0.367–0.569 <0.001
PG-SGA
 0–1 vs 2–3 vs 4–8 vs ≥9 2.128 1.855–2.440 <0.001
Type of lung cancer
 NSCLC vs SCLC 3.501 2.824–4.339 <0.001
TNM stage
 III B vs IV 1.144 0.932–1.405 0.197
Smoking condition
 Yes vs no 0.943 0.694–1.281 0.707
Anemia
 Yes vs no 1.125 0.922–1.373 0.245
BMI (kg/m2)
 <18.5 vs ≥18.5 and <25.0 vs ≥25.0 1.098 0.960–1.256 0.173
Pre-albumin (mg/dL)
 <20 vs ≥20 1.038 0.843–1.277 0.726
Albumin (g/L)
 <35 vs ≥35 0.562 0.451–0.700 <0.001
Multivariate analysis
Age (years)
 ≥60 vs <60 0.758 0.556–1.003 0.079
Sex
 Male vs female 0.338 0.259–0.441 <0.001
PG-SGA
 0–1 vs 2–3 vs 4–8 vs ≥9 1.857 1.583–2.180 <0.001
Type of lung cancer
 NSCLC vs SCLC 2.805 2.241–3.510 <0.001
Albumin (g/L)
 <35 vs ≥35 0.687 0.548–0.861 0.001

Abbreviations: BMI, body mass index; NSCLC, non-small-cell lung cancer; OS, overall survival; PG-SGA, Patient-Generated Subjective Global Assessment; SCLC, small-cell lung cancer.