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. 2019 Mar 19;11:2215–2223. doi: 10.2147/CMAR.S190642

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© 2019 Wang et al. This work is published and licensed by Dove Medical Press Limited

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OGT suppression promotes RCC cell apoptosis and inhibits the cell cycle.

Notes: (A–C) Apoptotic rates in 786-O and A498 cells as measured by flow cytometry following OGT knockdown. (D–G) Effects of OGT knockdown on cell cycle distribution in T24 and UMUC-3 cells, as determined by flow cytometry. Data are mean ± SD from three independent experiments. *P<0.05.

Abbreviations: FITC, Fluorescein isothiocyanate; OGT, O-GlcNAc-transferase;NC, negative control; PI, propidium iodide; RCC, renal cell carcinoma.