Table 1.
Variables | n | BCS (%) | MAST (%) | P-value |
---|---|---|---|---|
| ||||
Age (years) | <0.001 | |||
<50 | 8,943 | 5,148 (22.7) | 3,795 (32.3) | |
≥50 | 25,504 | 17,533 (77.3) | 7,971 (67.7) | |
Race/ethnicity | <0.001 | |||
Non-Hispanic White | 26,417 | 17,607 (77.6) | 8,810 (74.9) | |
Non-Hispanic Black | 2,481 | 1,617 (7.1) | 864 (7.3) | |
Hispanic (all races) | 2,578 | 1,684 (7.4) | 894 (7.6) | |
Other | 2,971 | 1,773 (7.8) | 1,198 (10.2) | |
Grade | <0.001 | |||
Well differentiated | 9,400 | 6,503 (28.7) | 2,897 (24.6) | |
Moderately differentiated | 18,510 | 12,137 (53.5) | 6,373 (54.2) | |
Poorly/undifferentiated | 6,537 | 4,041 (17.8) | 2,496 (21.2) | |
Unknown | ||||
Tumor stage | <0.001 | |||
T1 | 27,974 | 19,131 (84.3) | 8,843 (75.2) | |
T2 | 6,473 | 3,550 (15.7) | 2,923 (24.8) | |
PR status | <0.001 | |||
Negative | 3,485 | 2,189 (9.7) | 1,296 (11.0) | |
Positive | 30,962 | 20,492 (90.3) | 10,470 (89.0) | |
Chemotherapy | 0.002 | |||
No/unknown | 26,512 | 17,569 (77.5) | 8,943 (76.0) | |
Yes | 7,935 | 5,112 (22.5) | 2,823 (24.0) | |
21-gene recurrence score | <0.001 | |||
Low risk | 18,664 | 12,441 (54.9) | 6,223 (52.9) | |
Intermediate risk | 12,693 | 8,423 (37.1) | 4,270 (36.3) | |
High risk | 3,090 | 1,817 (8.0) | 1,273 (10.8) |
Abbreviations: MAST, mastectomy; PR, progesterone receptor; T, tumor; BCS, breast-conserving surgery.