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. Author manuscript; available in PMC: 2020 May 1.
Published in final edited form as: Cancer Lett. 2019 Feb 16;449:106–113. doi: 10.1016/j.canlet.2019.02.024

Figure 1. NFX1-123 expression in three dimensional raft cultures, cervical tissues, cervical precancerous lesions, and cervical cancer samples.

Figure 1.

(A) HFKs (B) 16E6/LXSN and (C) 16E6/FN123 HFKs were grown in raft cultures and stained for NFX1-123 protein. Overexpression of NFX1-123 in 16E6/FN123 HFKs had increased staining in basal and differentiating keratinocytes. (D) NFX1-123 stained throughout the normal cervical epithelium, with greater expression seen in upper differentiating keratinocytes. (E) HPV 16 positive cervical intraepithelial neoplasia 2 (CIN2) stained moderately for NFX1-123. (F) HPV 16 positive squamous cell carcinoma (SCC) stained highly for NFX1-123. (G) Rabbit IgG isotype control.