Fig. 4.
Association between endothelial glycocalyx damage and plasma levels of ADAMTS13, VWF antigen, A13/VWF ratio, and HNP1-3 protein following severe trauma. Plasma ADAMTS13 activity (A), VWF antigen (B), A13/VWF ratio (C), and HNP1-3 (D) in relation to the median or quartile values of plasma syndecan-1 were determined. Each dot represents a value from each individual patient. The lines within the dots are median ± 95% confidential interval (CI). Kruskal-Wallis (non-parametric) test was performed to determine the statistical significance among three groups. Signs *, **, ***, and **** indicate the p values <0.05, <0.01, <0.005, and <0.0001, respectively. n.s. indicates no statistically significant difference.