Fig. 5.
Effects of treadmill exercise on cell proliferation and neurogenesis in the hippocampal dentate gyrus. (A) Doublecortin (DCX)-positive cells in the hippocampal dentate gyrus. Upper panel: Photomicrographs of DCX-positive cells. The scale bar represents 50 μm. Lower panel: The number of DCX-positive cells in each group. (B) 5-Bromo-2’-deoxyuridine (BrdU)-positive cells in the hippocampal dentate gyrus. Upper panel: Photomicrographs of BrdU-positive cells. The scale bar represents 50 μm. Lower panel: The number of BrdU-positive cells in each group. WT, wildtype group; WT-EX, wildtype with treadmill exercise group; TG, BMAL1-transgenic group; TG-EX, BMAL1-transgenic with treadmill exercise group. The data are represented as mean±standard error of the mean. *P<0.05 compared to the WT. #P<0.05 compared to the TG.