Table 2. Description of GWAS meta-analysis on cardiometabolic disorders.
| Trait | Consortium | Sample size |
|---|---|---|
| Coronary artery disease | UK Biobank/CardiogramplusC4D [23] | 122,733 cases / 424,528 controls |
| Fasting glucose | MAGIC [15] | 133,010 |
| Fasting insulin | MAGIC [16] | 108,557 |
| Proinsulin | MAGIC [17] | 10,701 |
| Type 2 diabetes | DIAGRAM [19] | 26,676 cases / 132,532 controls |
| Blood pressure | UK biobank [20] | 140,000 |
| Total cholesterol | ENGAGE [21] | 100,184 |
| Triglycerides | ENGAGE [21] | 96,598 |
| HDL cholesterol | ENGAGE [21] | 99,900 |
| LDL cholesterol | ENGAGE [21] | 95,454 |
MAGIC: Meta-analysis of Glucose and Insulin-related traits Consortium; DIAGRAM: Diabetes Genetics Replication and Meta-analysis; CARDIOGRAMplusC4D: Coronary Artery Disease Genome wide replication and Meta-analysis plus Coronary Artery Disease; HDL: High density lipoprotein; LDL: Low density lipoprotein