Table 5. DNA methylation, blood pressure and HDL.
CpG site | Gene | Trait | Effect | P-value* |
---|---|---|---|---|
cg08462942 | ATG4B | Systolic blood pressure | -0.00026 | 2.0×10−13 |
cg06006530 | -0.0019 | 1.5×10−7 | ||
cg02710553 | ULK1 | Systolic blood pressure | -0.0018 | 4.5×10−7 |
Diastolic blood pressure | -0.0018 | 1.0×10−6 | ||
cg10819350 | ATG4D | HDL-cholesterol | -0.0158 | 3.2×10−5 |
*Adjusted for age, sex, cell counts, batch effects, anti-hypertensive and lipid-lowering medication
HDL: high density lipoprotein, significance threshold: 5.63×10−5