Fig 2. Sequence comparison and distribution of distal regulatory elements in the bovine CYP3A28 F3 fragment and human CYP3A4 promoter region.

Identical nucleotides are denoted by asterisks. The sequence is numbered relative to the transcription start site taken as +1. The newly identified bovine elements (C/EBPα) are bolded and underlined. The DR5 element, identified in both species through NUBIscan analysis, is highlighted in grey colour and boxed.